Mean ± SEM values of PT and aPTT after endotoxin administration and infusion of TFPI or placebo.

Endotoxin (4 ng/kg) was given as a bolus injection at t = 0. Infusion of TFPI (○) or placebo (▵) started at t = 0 and was continued until t = 6 hours. P values indicate the differences in results of TFPI and placebo experiments.