Kaplan-Meier survival curves for patients classified by the staging system of Durie and Salmon.

The solid line represents high syndecan-1 levels (≥ 1170 units/mL), and the dotted line represents low syndecan-1 levels (< 1170 units/mL). Open circles represent censored patients. (A) Patients in Durie-Salmon16 stages I and II were separated by high syndecan-1 levels (n = 21) and low syndecan levels (n = 68),P = .20). (B) Patients in Durie-Salmon stage III were separated by high syndecan-1 levels (n = 37) and low syndecan-1 levels (n = 48), P = .0006.