Schematic structures of the HK deletion mutants of D5 and D6 and inhibition of endothelial proliferation.

The HG-rich (light gray) and HGK-rich (black) regions of D5 and D6 (dark gray) are shown. Deletions are represented by a line. Mutants are fused to glutathione-S-transferase (GST) at the N-terminal. GST without HK sequence is indicated by a line. The bottom construct is a synthetic peptide from D6.