Generation of megakaryocytes in cultures of CD34⁺ cells infected with HCMV.

Purified CD34⁺ cells were either HCMV infected or mock infected and were cultured in the presence of thrombopoietin. Upper panel: Total increase in cell number per culture of uninfected (▪) and infected (•) cultures. Lower panel: Total number of megakaryocytic cells, based on the expression of CD42a antigen specific for megakaryocytic lineage in uninfected (▪) and infected (•) cultures.