Human light chain is detectable in serum from MM-engrafted mice.

Representative analysis of sera from control mice, mice injected IC with human myeloma, a mouse injected IO with human myeloma, and from a secondary recipient mice injected with BM from primary MM-engrafted mice was analyzed by ELISA for human kappa and lambda light chain. The black histograms represent expression of kappa light chain and gray bars represent expression of lambda light chain. Normal mouse serum was from uninjected mice.