Fig. 1.
![Fig. 1. MLL is fused in-frame to the AF3p21 in the t(3,11) (A) Genomic sequences of the MLL,MLL-AF3p21 (derived from the derivative chromosome 11[der(11)]), and AF3p21 genes at the breakpoint region. / (B) Sequence of the der11 MLL-AF3p21 fusion junction amplified by RT-PCR. (C) Schematic diagram of the consequences of the MLL, MLL-AF3p21, and AF3p21 proteins.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/95/3/10.1182_blood.v95.3.1066.003k11_1066_1068/6/bloo0031101z.jpeg?Expires=1724173428&Signature=LVjpY~01fSGNCLf4Pzt~ouSBBw9z3FJ8LFX1GmpiRrpNpqX9vzJB9uOs4PpyrvNROvx0veLbzb5zH~pt92SgUB7S1wCDVrZTwYWqrHadOkRqhzYRgL9AENF2BtRJyFrb5TRflG4vf4feo7HneKUtz9m~7lOZwEiT1J18Sc9RIB4ueBSOFjg1P-BH82oLjVJfu9myFslLybWiyP~uhuJlby8gz39cVWekE48D1HddEZCDIrGdMlLaNXViNY9GRcIphMQa3aZI6g6FB-8vkdmoMAOV9vaAjs0OvZJu2SL-6xUxugjhP5E4fervQ33dKlD~d20vRQE-NBhWXeJ3cJGmIQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
MLL is fused in-frame to the AF3p21 in the t(3,11) (A) Genomic sequences of the MLL,MLL-AF3p21 (derived from the derivative chromosome 11[der(11)]), and AF3p21 genes at the breakpoint region.
(B) Sequence of the der11 MLL-AF3p21 fusion junction amplified by RT-PCR. (C) Schematic diagram of the consequences of the MLL, MLL-AF3p21, and AF3p21 proteins.
