Loss of p27 is associated with poor survival in mantle cell lymphoma.

Kaplan-Meier curve for overall survival of p27+ (open squares) and p27− (open circles) in MCL. Survival curves in p27+/p53− (open squares), p27−/p53− (open circles), p27−/p53+ (full triangles), and p27+/p53+ (open diamonds) in patients with MCL (panel B).