Maximum response on sequential analysis for the 54 CML patients in CR on IFN.

For the 14 patients who relapsed, the minimum BCR-ABL/ABL ratio achieved was significantly higher (P < 0.0001, 2-sided Mann-Whitney test) than that seen in patients who remained in CR. ▵ = relapse in chronic phase CML, n = 11; ▴ = relapse in blast crisis, n = 3; □ = continuing complete remission, n = 40.