Demonstration of von Willebrand factor (vWF) binding to the Thr-145 and Met-145 forms of glycoprotein (GP)Ib with the use of resonant mirror technology.

Recombinant GPIbα-calmodulin was coupled to bovine serum albumin-peptide immobilized on the carboxymethylated dextran surface and binding of vWF to both forms of GPIbα measured.