Fig. 5.
Photosensitization with verteporfin and red light causes productive κB activation.
HL-60 cells transfected with a κB-luciferase reporter plasmid construct were treated with either tumor necrosis factor-α (200 U/mL) or verteporfin (5 ng/mL) followed by red light (2 J/cm2) irradiation. Luciferase activity was determined 24 hours later. Results are given as the ratio of luciferase activity for cells maintained in medium alone. Means with standard deviations for the results of 3 independent experiments are shown.
