Fig. 5.
![Fig. 5. APC from anti-CD3ɛ–treated mice support the growth of the Th2, but not Th1, Ag-specific clones. Spleen cells from control antibody-treated or anti-CD3ɛ–treated mice (50 μg IV) were irradiated and used as accessory cells to stimulate the Th1 clones AE.7 and CLOVA 1.1 or the Th2 clones HG.4 and CLOVA 2.9 in the presence of nominal Ag. Clones were also stimulated by Ag presented by G10-depleted splenic accessory cells for the sake of comparison. Results are expressed as cpm of [3H] TdR incorporation by responder cells. These results are representative of 3 independent experiments.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/94/12/10.1182_blood.v94.12.4347/5/blod42431005x.jpeg?Expires=1724239168&Signature=hMRs9bSC4ncdXhGPIoHksUPtyDWaG43qftJYp4cdJuCt6CxouYKCymxYhBTfeXyxU2o-CZFUo4Y3yZPBoOJgU6bGICJzC4XQrUc6XGTAFyYCwJDY~5KRocZoqT8masywQrBhKgbZ~jsdmAX5GdMoIeFaMV~wo5u4VpT8FhTOhCvRf72Uk3Ucbjhol9wjqH5kgy5n2wWL5X1wlCeVEgevSRE8wosJ-TyvCJYNwG2xkt5WkTLh-8UGmZA~HC76KkSsSEkCccEJbRao2UG9-rNE-paXAAkC880S7BXPczvyP0Kcen~nBQ2SSeItqkBDQ4ZDmFBWw2yX~Dws0CB20ufMcQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
APC from anti-CD3ɛ–treated mice support the growth of the Th2, but not Th1, Ag-specific clones. Spleen cells from control antibody-treated or anti-CD3ɛ–treated mice (50 μg IV) were irradiated and used as accessory cells to stimulate the Th1 clones AE.7 and CLOVA 1.1 or the Th2 clones HG.4 and CLOVA 2.9 in the presence of nominal Ag. Clones were also stimulated by Ag presented by G10-depleted splenic accessory cells for the sake of comparison. Results are expressed as cpm of [3H] TdR incorporation by responder cells. These results are representative of 3 independent experiments.
