SDS-PAGE gelatin zymography of the CM of EA.hy926 endothelial cells either nonexposed (positive control) or exposed to each VBL dose for 24 hours. (A) White bands against a dark background corresponding to the gelatinolytic areas of the MMP-2 and MMP-9 activity. (B) MMP-2 activity measured by screening band intensity through computerized image analysis.