Fig. 2.
Time-course of human VEGF promoter activity in Hep3B cells.
The cells were exposed to the same conditions as Figure 1 for 12, 24, 36, 48, or 60 hours. All data within 24-60 hours are significantly greater than for controls (P < 0.01). n = 6 independent experiments. Fold induction by hypoxia or by SNAP represents the ratio of relative luc activity in cells at 1% O2, or 0.5 mmol/L SNAP in 0.1% DMSO, to those in 21% O2 or 0.1% DMSO, respectively.
