Fig. 6.
Enhanced homing of Ba/F3 cells to the spleen in the presence of SDF-1, in vivo. The splenic ratio of differently-labeled, fluorescent Ba/F3 and Ba/F3.p210BCR/ABL cells was determined 3 hours after injection into mice. Recipient mice spleens were injected with PBS (○) or recombinant SDF-1 (1μg; ◍) immediately before infusion of pooled cells. Ba/F3 cells homed more efficiently to the spleen than Ba/F3.p210BCR/ABL cells in the presence of SDF-1 (P < .05). The lines connecting circles indicate paired mice in 4 independent experiments.

Enhanced homing of Ba/F3 cells to the spleen in the presence of SDF-1, in vivo. The splenic ratio of differently-labeled, fluorescent Ba/F3 and Ba/F3.p210BCR/ABL cells was determined 3 hours after injection into mice. Recipient mice spleens were injected with PBS (○) or recombinant SDF-1 (1μg; ◍) immediately before infusion of pooled cells. Ba/F3 cells homed more efficiently to the spleen than Ba/F3.p210BCR/ABL cells in the presence of SDF-1 (P < .05). The lines connecting circles indicate paired mice in 4 independent experiments.

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