(A) Liver iron (total content or tissue concentration) and (B) duodenal iron in control and homozygous hypotransferrinemic mice; the latter group was either untransfused or given 1 to 3 transfusions of erythrocytes from control animals. All determinations were performed 3 days after the last transfusion except for the multiple-transfused group, which were performed 5 days postinjection. Data: mean ± SD for 5 to 10 animals in each group except for the (×1) transfused group where n = 3. *P < .04; **P< .001 as compared with the control group. $,P < .02 as compared with the nontransfused homozygous group.