Concentration-dependent inhibition of binding of¹²⁵I-PfEMP1 to CD36 and ICAM-1. (A) Inhibition of binding to CD36 using MC R⁺ SDS extract was performed as in Fig1. Peptide concentration is given in μmol/L. The concentration of peptide CD36 397-409 was 500 μmol/L. (B) Inhibition of binding to ICAM-1 using ItG-ICAM SDS extract was performed as in Fig 1, except that the peptides were preincubated with the extract for 1 hour at room temperature. Peptide concentration is given in μmol/L and all samples (except No DMSO) had a 5% final concentration of DMSO. The percent inhibition of binding from the DMSO control is indicated at the bottom of the figure.