American Society of Hematology

Fig. 4.

$Fig. 4. Repopulation in nonablated FACKO mice. (A) A cohort of FACKO mice were injected with 1 × 106 unfractionated wild-type cells. Mice A, B, C, and D were treated with a single intraperitoneal injection of 10 μg MMC. Mouse E was untreated. The lines connecting data points indicate the trend of change. (B) Phosphoimager data corresponding the data in (A) before and after (+) MMC treatment. (C) Wild-type recipients were radio-ablated and transplanted with bone marrow cells from a treated nonablated transplant recipient (1, 2, and 3) or from an untreated nonablated transplant recipient (4, 5, 6, and 7).$

Repopulation in nonablated FACKO mice. (A) A cohort of FACKO mice were injected with 1 × 10⁶ unfractionated wild-type cells. Mice A, B, C, and D were treated with a single intraperitoneal injection of 10 μg MMC. Mouse E was untreated. The lines connecting data points indicate the trend of change. (B) Phosphoimager data corresponding the data in (A) before and after (+) MMC treatment. (C) Wild-type recipients were radio-ablated and transplanted with bone marrow cells from a treated nonablated transplant recipient (1, 2, and 3) or from an untreated nonablated transplant recipient (4, 5, 6, and 7).

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