Fig. 4.
![Fig. 4. Effect of the MEK inhibitor on DNA synthesis capacity of CD34+ cells grown with rhuMGDF. Cells from cultures performed in the absence (▪) or presence (▨) of 6 μmol/L PD98059 were harvested at the indicated days and DNA synthesis was assessed by measuring [3H]thymidine incorporation. Results are mean ± SD of triplicate determinations from a representative experiment of 3 performed. The relative increase in [3H]thymidine incorporation in PD98059-treated cells as compared with control DMSO-treated cells is indicated below the bars for each time point.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/94/5/10.1182_blood.v94.5.1601/5/blod41719004x.jpeg?Expires=1723934254&Signature=nRAIQdZ2l7ONQ7EesyZP5EMkpLH3kMnY~ILVCoiTsf1e1VkQFC1EoQTEESv8OFxljl9JL8CoidzBJn6aN2uZ0D3w1KRqelecMfu4W0YWdrs7POC9gCZRA4OSDDe9eBPbubxMhVHDJydfwFTkdPfy-tOUe2auUEIW2g~mmewu14lKWjz~CTIY~QDS9bcklBA1DlFf-hQNz~wn8R3sDsIczqflN9w7BdP-n-aPAYQFDYxrxoN-EMUJB3xtRVGnjfuIVwh9x0wKIZDnUKqYdtkKKrPq6pdaBWekEbsTIzAqlSPBeL6YNnVgDz59hyUEFF5k~gGgAcfJz5AMi3J2-IjSwg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of the MEK inhibitor on DNA synthesis capacity of CD34+ cells grown with rhuMGDF. Cells from cultures performed in the absence (▪) or presence (▨) of 6 μmol/L PD98059 were harvested at the indicated days and DNA synthesis was assessed by measuring [3H]thymidine incorporation. Results are mean ± SD of triplicate determinations from a representative experiment of 3 performed. The relative increase in [3H]thymidine incorporation in PD98059-treated cells as compared with control DMSO-treated cells is indicated below the bars for each time point.
