Adhesion of human platelets in response to 90 minutes of ischemia and subsequent reperfusion. Human platelets derived from healthy human subjects or from a patient suffering from Glanzmann’s disease ( _IIb/β₃−/−) were labeled with rhodamine-6G and transfused into wild-type mice. Platelet-endothelial cell interactions were investigated in arterioles (A) and venules (B) using IVM. Sham-operated animals served as controls. The number of adherent platelets is given per mm² vessel surface. Mean ± SEM, n = 6 experimental animals per group. *P < .01v sham, Dunn’s method.