Patient CHEB, kidney biopsy. (A) Immunofluorescence microscopy, anti-κ conjugate (original magnification × 500), heavy staining of cytoplasmic inclusions in proximal tubular cells. (B) Electron microscopy (original magnification × 2,600): numerous crystalline and osmiophilic inclusions in the cytoplasm of proximal tubular cells. (C) Electron microscopy (original magnification × 16,000): details of intracytoplasmic crystalline inclusions.