Fig. 1.
![Fig. 1. Effect of retinoic acid on DNA synthesis. Human B cells were isolated and stimulated with μ (37.5 μg/mL) and SAC (0.005%) as described in Material and Methods. Cells (0.75 × 106 cells/mL) were cultured in 96-well culture plates in triplicates. Retinoic acid (10 or 1000 nmol/L) was added at the indicated times (T) after stimulation. [3H]Thymidine incorporation (mean ± SD) was measured as described in Material and Methods. One representative experiment of three is shown. μ, F(ab′)2 fragment of rabbit antihuman IgM; SAC,Staphylococcus aureus crude cell suspension; RA, retinoic acid.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/94/4/10.1182_blood.v94.4.1348/4/blod41629001x.jpeg?Expires=1724241185&Signature=slp1BD7LhgIsIXZiA29IsXUzwUuqo0pcFtMetgraBWjC4mWa--fzIHTcJk~rjznHbbDQJbK69h3HAXti3dCfNRGA26GghCh21jZC7BsoybqEMcTtjq9hcWI458B9-dsq2TvSxq8o0OduQ-NVU-NyCaXAVwTEyS9Dh89VjcU6cllm5GnnpGR0vXrhPhxe2GpX9kXpud5pJ5-ABvlyycC4af~bafqYJQ4LVfEhelaxGE0KlkEJahKbnG~shID8HIUnLdFREbXVgT90zIq-dG4g3V-jDcxmyysdS1EcFLZVw10nayYVwIYblN6LyVWjvnZL2eazpO-EH64KfsnSbvVCIg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of retinoic acid on DNA synthesis. Human B cells were isolated and stimulated with μ (37.5 μg/mL) and SAC (0.005%) as described in Material and Methods. Cells (0.75 × 106 cells/mL) were cultured in 96-well culture plates in triplicates. Retinoic acid (10 or 1000 nmol/L) was added at the indicated times (T) after stimulation. [3H]Thymidine incorporation (mean ± SD) was measured as described in Material and Methods. One representative experiment of three is shown. μ, F(ab′)2 fragment of rabbit antihuman IgM; SAC,Staphylococcus aureus crude cell suspension; RA, retinoic acid.
