Flow cytometry analysis of peripheral blood cells of C57BL/6 (A and B) and SAD (C and D) mice with Sca-1 and lineage-specific antibodies. The enclosed boxes depicted in (A) and (C) represent the total Sca-1⁺ cells from the entire cell population analyzed. (B) and (D) subdivide the Lin^- and Lin⁺ cells from the total Sca-1⁺ cell population. The quantity of Sca-1⁺Lin⁻multipotent progenitor cells in SAD (0.8%) is increased by 4-fold compared with control mouse (0.2%).