TIA-1⁺ cells increase significantly within regressing skin lesions during rhIL-12 treatment. (A) Involved skin at baseline from patient 8 with small numbers of TIA-1⁺cells as indicated by the arrow. (B) A 2- to 3-fold increase in the proportion of TIA-1⁺ cells as indicated by the arrows within the same lesion during regression associated with rhIL-12 treatment.