Effect of administration of endotoxin (A) or DDAVP (B) on vWF (•) and propeptide levels (○) in healthy individuals. Endotoxin (4 ng/kg body weight) or DDAVP (0.4 μg/kg body weight) were administered at time 0. The endotoxin study group consisted of 8 subjects, the DDAVP study group of 9 subjects. Data points represent the mean and bars the SEM.