American Society of Hematology

Fig. 2.

$Fig. 2. Enteropathic mucosa from cases of (A) gluten-responsive celiac disease, (B) refractory sprue, (C) ulcerative jejunitis, and (D) EATL sequentially immunostained for CD8 (peroxidase-brown) and CD3 (alkaline phosphatase-blue). In (A) IEL are predominantly CD8+ (brown) with only occasional CD3+, CD4/8− (blue) cells. Note predominance of CD3+, CD4+ (blue) cells in the lamina propria. In (B through D), most IEL are CD3+, CD4/8− (blue) with only occasional CD8+(brown) cells.$

Enteropathic mucosa from cases of (A) gluten-responsive celiac disease, (B) refractory sprue, (C) ulcerative jejunitis, and (D) EATL sequentially immunostained for CD8 (peroxidase-brown) and CD3 (alkaline phosphatase-blue). In (A) IEL are predominantly CD8⁺ (brown) with only occasional CD3⁺, CD4/8⁻ (blue) cells. Note predominance of CD3⁺, CD4⁺ (blue) cells in the lamina propria. In (B through D), most IEL are CD3⁺, CD4/8⁻ (blue) with only occasional CD8⁺(brown) cells.

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