Summary of chimerism in recipient mice transplanted withFancC −/− or FancC +/+ test cells. Chimerism of peripheral blood cells was determined by fluorescence cytometry for mice transplanted with FancC −/− (▪) or FancC +/+ (•) Sca1⁺lin^−/dim cells and 500,000 competitor cells. The mean chimerism for each Sca1⁺lin^−/dim cell number transplanted was calculated for each genotype, and the data generated at 1, 3, and 6 months after transplantation are summarized in the graphs as indicated. The error bars represent standard error of the means. Twelve mice (six per genotype) were transplanted at each test cell concentration. *P < .05 FancC −/− cells exhibit a significant decrease in repopulating ability as compared with FancC +/+cells over several Sca1⁺lin^−/dim cell doses transplanted at every time point evaluated.