vIL-6 induces VEGF secretion. (A) Detection of VEGF in the culture supernatant of parental NIH3T3 cells, vector control (BN7), and stable clones of vIL-6 transfectants (v6H, v6I, and v6O). (B) Effects of anti–vIL-6 Ab (10 μg/mL) on VEGF detection in the culture supernatant of v6O and BN7 cells. Data represent the mean (±SD) of triplicates in one representative experiment of three performed.