Fig. 5.
Fig. 5. HIV-1LAI replication by mature DC. Culture day 8 sorted CD1a+ DC were cultured for 48 hours under standard conditions plus CD40LT, and they were then exposed to HIV-1Ba-L (○) or to HIV-1LAI (□). Virus production is expressed as geometric mean ± SD ng p24/105viable cells of three experiments. The p24 levels in HI virus-exposed DC were always <0.1 ng/105 viable cells; levels in HIV-1LAI– and HIV-1Ba-L–infected cultures were significantly different as assessed by two-way analysis of variance (P = .0015).

HIV-1LAI replication by mature DC. Culture day 8 sorted CD1a+ DC were cultured for 48 hours under standard conditions plus CD40LT, and they were then exposed to HIV-1Ba-L (○) or to HIV-1LAI (□). Virus production is expressed as geometric mean ± SD ng p24/105viable cells of three experiments. The p24 levels in HI virus-exposed DC were always <0.1 ng/105 viable cells; levels in HIV-1LAI– and HIV-1Ba-L–infected cultures were significantly different as assessed by two-way analysis of variance (P = .0015).

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