Fig. 7.
Fig. 7. Sequence of the Vκ3 gene rearrangement, including part of the promoter region, the leader intron, and part of the constant region. Sequence format is the same as in Fig 6. The sequence obtained from L1236 cells is compared with germline sequences for the corresponding Vκ, Jκ, and Cκ genes (L2,22Jκ1,23 and Cκ24). The aberrant splicing of the leader intron is indicated. The sequence of Jκ1 and Cκ was obtained from cDNA. Therefore, the intron sequence between Jκ1 and Cκ is not given. The Jκ gene is correctly spliced to the Cκ gene. This sequence is available from the EMBL database under accession no.AJ005571.

Sequence of the Vκ3 gene rearrangement, including part of the promoter region, the leader intron, and part of the constant region. Sequence format is the same as in Fig 6. The sequence obtained from L1236 cells is compared with germline sequences for the corresponding Vκ, Jκ, and Cκ genes (L2,22Jκ1,23 and Cκ24). The aberrant splicing of the leader intron is indicated. The sequence of Jκ1 and Cκ was obtained from cDNA. Therefore, the intron sequence between Jκ1 and Cκ is not given. The Jκ gene is correctly spliced to the Cκ gene. This sequence is available from the EMBL database under accession no.AJ005571.

Close Modal

or Create an Account

Close Modal
Close Modal