(A) All of the TRF measurements as a function of time for all of the pediatric patients is shown. (B) TRF measurements as a function of time plotted for the pediatric patients are shown. TRF measurements obtained at times <1 month after birth are omitted from this figure because some patients showed increases in TRF length in the immediate postnatal period. Least squares linear regression lines are plotted for each of the patients. Symbols for (A) and (B): (□), patient 1; (◊), patient 2; (○), patient 3; (▵), patient 4; (⊞), patient 5; (▨), patient 6; (⊕), patient 7; (▿), patient 8; (┌), patient 9. (C) TRF lengths for the nine pediatric patients were predicted from the equations of the lines of (B) and plotted for the 1-month and 36-month time points. (D) TRF lengths as a function of age were plotted for two uninfected adult patients. (E) TRF lengths as a function of age were plotted for all of the points obtained from our two adult patients and for the TRF length obtained at the oldest available age for each of our pediatric patients.