Induction of apoptosis mediated by daunorubicin, doxorubicin, and etoposide is independent of CD95 receptor signaling. Jurkat (——, ⧫) or Jurkat-R cells (-----, ◊) were stimulated with (A) daunorubicin, (B) doxorubicin, and (C) etoposide at the indicated concentrations. Assessment of hypodiploid apoptotic nuclei was performed as described in Fig 1.