Schema for Total XII protocol continuation therapy. Abbreviations: P, prednisone; V, vincristine; D, daunomycin; Asp,Escherichia coli asparaginase; VM, teniposide; ARA-C, cytarabine; HDMTX, high-dose methotrexate; 6MP QD, daily oral 6-mercaptopurine; Mtx QWK, methotrexate given IV or IM every week; CNS, central nervous system; IT MHA, intrathecal methotrexate, hydrocortisone, and cytarabine.