Changes in L-selectin expression on PMN in the circulation after IV injection of either 2.0 mg/kg dexamethasone (n = 7) or saline (n = 6). Values are expressed as the means ± SEM of mean fluorescence intensity. Dexamethasone decreased L-selectin on circulating PMN with no change in control rabbits. The effect of dexamethasone to decrease L-selectin became detectable only at 12 hours after treatment. *P < .01 compared with control; Dex, dexamethasone.