Fig. 3.
![Fig. 3. CTL activity in mice immunized with irradiated cells and GM-CSF/IL-12–expressing vaccine. Mice were immunized with irradiated only or irradiated, GM-CSF/IL-12–transfected cells (MPC11 [A] or MPC11Dox10-1 [B]). At day 21 after the initial vaccine injection, animals were killed, and CTL activity was tested as described in Materials and Methods. CTL activity is expressed as the percentage of specific lysis of 51Cr-labeled target cells. Each value represents mean of duplicate samples. The error between duplicates was less than 10%. The experiments were repeated twice with similar results.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/93/6/10.1182_blood.v93.6.1831.406k38_1831_1837/5/blod40638003x.jpeg?Expires=1725165043&Signature=11bkIyP2A4LqXUvRhh5HFT1CwBN4Av4zDJHpCFt6a3iyr5dpblJEaQRPuSe2HT6Veh0qLlMp9S~9jA9yTU5whOvYeYqCAn-vbXB9B74CxfKXn1w3yxqZpS3t1H4GAAFegaQF-M8xLUKYDSZvGUxyXeuSLA23qjbr33Zmh2xo6qTdpOXe98hd6Xl1iimEs9vAFPwjEAPVWPVyVVRO0QjUh3M~Ibun1zTRD2bBdM3zglWvZAhicDTzl2DC1W7xOKLIJfhLXuU1Sr5OKuZy3fWpt0UuYf3FFNwmddTGYx3mjqxMDIjTBuFA0x~MQnuFlEBIAOjc-mRHS~zkILPngZ3eCg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
CTL activity in mice immunized with irradiated cells and GM-CSF/IL-12–expressing vaccine. Mice were immunized with irradiated only or irradiated, GM-CSF/IL-12–transfected cells (MPC11 [A] or MPC11Dox10-1 [B]). At day 21 after the initial vaccine injection, animals were killed, and CTL activity was tested as described in Materials and Methods. CTL activity is expressed as the percentage of specific lysis of 51Cr-labeled target cells. Each value represents mean of duplicate samples. The error between duplicates was less than 10%. The experiments were repeated twice with similar results.
