American Society of Hematology

Fig. 2.

$Fig. 2. Annexin V stained FN-adhered myeloma cells have a lower apoptotic fraction compared to nonadhered cells following acute drug exposure. 8226/S myeloma cells were exposed to 1 μmol/L doxorubicin for 1 hour (A) or 50 μmol/L melphalan for 24 hours (B), stained by Annexin V 24 hours later, then analyzed by flow cytometry. Histograms are adjusted for background staining in untreated cells, bars are the SD of three different experiments; ∗, P < .05.$

Annexin V stained FN-adhered myeloma cells have a lower apoptotic fraction compared to nonadhered cells following acute drug exposure. 8226/S myeloma cells were exposed to 1 μmol/L doxorubicin for 1 hour (A) or 50 μmol/L melphalan for 24 hours (B), stained by Annexin V 24 hours later, then analyzed by flow cytometry. Histograms are adjusted for background staining in untreated cells, bars are the SD of three different experiments; ∗, P < .05.

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