American Society of Hematology

Fig. 4.

$Fig. 4. The reversibility of heparin’s effects on osteoclast surface and erosion depth. Rats were injected with vehicle alone (open bars) or unfractionated heparin at a concentration of 0.5 U/g/day (cross-hatched; rising to the right) or 1.0 U/g/day (cross-hatched; rising to the left). On day 28, half of the rats from each group were killed while the other half were allowed to live for an additional 28 days with no further treatment before determining osteoclast surface (A) and/or erosion depth (B). Data are expressed as mean ± SEM. * P < .005 when compared with either baseline or control values for both (A and B).$

The reversibility of heparin’s effects on osteoclast surface and erosion depth. Rats were injected with vehicle alone (open bars) or unfractionated heparin at a concentration of 0.5 U/g/day (cross-hatched; rising to the right) or 1.0 U/g/day (cross-hatched; rising to the left). On day 28, half of the rats from each group were killed while the other half were allowed to live for an additional 28 days with no further treatment before determining osteoclast surface (A) and/or erosion depth (B). Data are expressed as mean ± SEM. * P < .005 when compared with either baseline or control values for both (A and B).

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