Fig. 11.
![Fig. 11. Biological activity of OSM produced by PMN. HepG2 cells were incubated with the supernatant from LPS- plus GM-CSF–stimulated PMN (PMN conditioned medium [CMP]) or rhOSM (10 ng/mL); control cells (CTRL) were cultured in the medium alone. Anti-OSM antibodies were used as indicated. Secreted 1-acid glycoprotein (AGP) was determined in cell-free supernatants after 24 hours (nanograms per microgram of DNA). Results are expressed as the mean ± SEM of five independent experiments. *P < .05 compared with control cells. #P< .05 compared with AGP synthesis without anti-OSM.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/93/4/10.1182_blood.v93.4.1413/5/blod40406011x.jpeg?Expires=1724243279&Signature=G18ZJYsAybZijoeXFEz5RRGbzT5JVYg7G~JxMPK6Hx92oVirWvA2L7pisOopHYIITclUnwf1bcR~kf~vrfXZKRCNHpsl3L7Wl5JIP-~eLEYCfTRfR~9-iEfFwccu1ImgU~f7-ZZtVL5i4~4Sy3vrRmJCVJuLI7EaLd6U~ZxIrc5DLWvbLwhUQQYmFVM9NBcew9WjgesZwRRnfzrSgPj0nkPDc6SZ05z0mSgRkQ-f2vSgu7ESIWRlLnPud0VVCXMtTcCZEzSfMpdrMA0RyrNX60FQwZ6gBxCssfmHzrOJZoqlPQhu1Q8vNiS305X0ZlGWk6x8QFYEWPrkdIrTNA0Bbw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Biological activity of OSM produced by PMN. HepG2 cells were incubated with the supernatant from LPS- plus GM-CSF–stimulated PMN (PMN conditioned medium [CMP]) or rhOSM (10 ng/mL); control cells (CTRL) were cultured in the medium alone. Anti-OSM antibodies were used as indicated. Secreted 1-acid glycoprotein (AGP) was determined in cell-free supernatants after 24 hours (nanograms per microgram of DNA). Results are expressed as the mean ± SEM of five independent experiments. *P < .05 compared with control cells. #P< .05 compared with AGP synthesis without anti-OSM.
