Fig. 3.
![Fig. 3. Plot summarizing data from multiple experiments. ERK2 and MEK1 activities were measured as described in Fig 2 and the fold activation was calculated by normalizing to activities measured in untreated controls (− CSF-1) or to activities in samples treated with CSF-1 only (+ CSF-1) using the formula 1+ ([with cAMP] − [no cAMP])/([no cAMP] − [untreated]). Data shown represent the means ± SE, with the number of experiments (n) indicated. Statistically significant differences between untreated and cAMP-treated pairs are denoted by asterisks: *P < .05; **P < .001.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/93/2/10.1182_blood.v93.2.537/4/blod40230003x.jpeg?Expires=1724940871&Signature=PXpKqDoActd7pty3pbjhL2uTEdgKZh2jWysiUig43RO11HbtRKG96FtTGWv53e~rXFqft~LdkTND45KPogcsRXoUwWllR7YVjFJfE6dQGrJHkh1nUGp13mqxp75vbrcqtonOZOS7SHzxhWS--XhqRj4FWLar-cZ7s2vxMbE08yNkKobGHOIrwa3M1CHAH5U5W9dY4B~O3sBGrS8bpn0s~G2VdqBY4TFDyLhZXU2waOOc292~OnVkyHufyEv-DLUeJ0soAQdI00CxXKPZ23uOWQv-7vB-BLJEn68xuEwWUO7dGKPiJYgfvjWMl3JOqu4kS29F33vbtwH2EMpI0uY5-A__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Plot summarizing data from multiple experiments. ERK2 and MEK1 activities were measured as described in Fig 2 and the fold activation was calculated by normalizing to activities measured in untreated controls (− CSF-1) or to activities in samples treated with CSF-1 only (+ CSF-1) using the formula 1+ ([with cAMP] − [no cAMP])/([no cAMP] − [untreated]). Data shown represent the means ± SE, with the number of experiments (n) indicated. Statistically significant differences between untreated and cAMP-treated pairs are denoted by asterisks: *P < .05; **P < .001.
