Fig. 1.
![Fig. 1. IL-10 suppression of SEB stimulation: SEB dose-response. PBMCs were added to 96-well plates at 3 × 105 cells/mL along with IL-10 at 10 U/mL or media only. After 2 days of incubation, media alone or SEB at varying concentrations was added and plates were further incubated for another 2 days. Proliferation was measured by [3H]thymidine incorporation. Different PBMC donors are represented in each experiment. Data are expressed as the mean CPM ± SD. Results were determined to be statistically significant by the Student’s t-test (P < .002). Numbers between curves indicate the percentage of suppression by IL-10.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/93/1/10.1182_blood.v93.1.208/5/blod40106001x.jpeg?Expires=1724999854&Signature=R3wEi4xmepnYOAHhAGRGAxuCO~KokJbDVTfGhGCg6we2wkOx8svLfE11Mrmn065k~SKRmMUDTVfD74WpyG2gLLib3fLAIz7KUOWyPSHTRG9h4-MHsto4VULf~ujBM6RuQ2K4Ur-4XGlU1MHI~fPZXE7Rbboet8MPo2ZqHMg-F5VxFKPZ~CHkk-bQm3186b7HYh9icqeylirSL3XmAX~5xJ6JmAnGIIbHEfA4HtOSYnX2ZD883V4p96cmylRPMT4aSTnioasXOuu9rKqkYJqpg~2fDLI7q7WsQwZK1D7vNSPTrWgNjwoN4sSECHb-WOcUIj88Yft1FRREf9-Mzg6u1w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
IL-10 suppression of SEB stimulation: SEB dose-response. PBMCs were added to 96-well plates at 3 × 105 cells/mL along with IL-10 at 10 U/mL or media only. After 2 days of incubation, media alone or SEB at varying concentrations was added and plates were further incubated for another 2 days. Proliferation was measured by [3H]thymidine incorporation. Different PBMC donors are represented in each experiment. Data are expressed as the mean CPM ± SD. Results were determined to be statistically significant by the Student’s t-test (P < .002). Numbers between curves indicate the percentage of suppression by IL-10.
