Comparison of the quantitative follow-up of FMLP-induced (10−4 mol/L) oxygen radical production by isolated neutrophils in the postoperative/posttraumatic period between the study group and the control group. Oxygen radical production was assayed by chemiluminescence measurements. Chemiluminescence response is expressed as a percentage of the baseline value, ie, chemiluminescence response at the first postoperative day (100%). In the study group, the baseline value at the first postoperative day represents the chemiluminescence response before infusion of rhG-CSF. Dosages of rhG-CSF administered in the study group are indicated as bars on the x axis. Each point of the curves is the mean ± SEM of the chemiluminescence response of the 10 patients of the study group and of the control group, respectively, at the various days. *P < .05 equals a statistically significant difference between chemiluminescence response at the first postoperative day, ie, baseline value, and the chemiluminescence response during the following days within the study group and within the control group, respectively. +P < .05 equals a statistically significant difference between the chemiluminescence response of the study group and that of the control group at the various postoperative days. (○) Study group; (×) control group. (Modified and reprinted with permission.51)
