Fig. 5.
Fig. 5. Induction of HGF-responsive CFU-c progenitors from EML cells. EML cells were induced to undergo myeloid differentiation according to the procedures described in Materials and Methods. (A) The total number of GM-CSF–responsive colonies generated from 1 × 105 EML cells cultured in SCF/atRA with or without IL-3. (B) The total number of EPO-responsive colonies generated from 1 × 105 EML cells cultured in SCF/atRA with or without IL-3. (C) The total number of SCF-responsive colonies generated from 1 × 105 EML cells cultured in SCF/atRA with or without IL-3. (▪) SCF + RA + IL-3; (•) SCF + RA.

Induction of HGF-responsive CFU-c progenitors from EML cells. EML cells were induced to undergo myeloid differentiation according to the procedures described in Materials and Methods. (A) The total number of GM-CSF–responsive colonies generated from 1 × 105 EML cells cultured in SCF/atRA with or without IL-3. (B) The total number of EPO-responsive colonies generated from 1 × 105 EML cells cultured in SCF/atRA with or without IL-3. (C) The total number of SCF-responsive colonies generated from 1 × 105 EML cells cultured in SCF/atRA with or without IL-3. (▪) SCF + RA + IL-3; (•) SCF + RA.

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