Experimental AIHA induced by MRBC antibodies in FcγRIII wild-type and FcγRIII KO mice. (A and B) Daily hematocrits of FcγRIII wild-type (□) and FcγRIII KO (▪) mice injected with the pathogenic MRBC MoAbs 105-2H (A) and 34-3C (B). No decrease of Ht level was observed for mice injected with nonpathogenic isotype control MoAbs (○). Ht values lower than 40% were considered as anemic. Shown are the mean values obtained from 5 to 10 mice in each group (SD <3%).