Partial restriction enzyme map of the 5′-flanking region of the endoglin gene. The top bar represents the 3.3-kbSacII/PvuII fragment containing the untranslated region (▨), the signal peptide encoding region (░), and part of the first intron (▪). The 741-bpBamHI/BbrPI fragment was cloned into the luciferase reporter vector pXP2. The schematic representation is approximately to scale.