American Society of Hematology

Fig. 8.

$Fig. 8. The plottings of the correlation between MDR1gene expression and methylation status of 5′CpG sites at theMDR1 promoter region in NPB and AML patients. X-axis is methylation status described as percent (%). Y-axis is MDR1gene expression described as fold compared with average value of NPB. (▵), NPB; (○), AML with CR; (•), AML with refractory; and (◍), AML M3 and AML with unknown outcome. The solid line was piecewise linear regression line. The value of methylation status at which the slope changed significantly was 25%.$

The plottings of the correlation between MDR1gene expression and methylation status of 5′CpG sites at theMDR1 promoter region in NPB and AML patients. X-axis is methylation status described as percent (%). Y-axis is MDR1gene expression described as fold compared with average value of NPB. (▵), NPB; (○), AML with CR; (•), AML with refractory; and (◍), AML M3 and AML with unknown outcome. The solid line was piecewise linear regression line. The value of methylation status at which the slope changed significantly was 25%.

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