Fig. 4.
Fig. 4. Trivalent antimonials induce apoptosis of APL cells. Untreated NB4 cells (A) or cells treated for 24 hours with either 1 μmol/L As2O3 (B), 1 μmol/L Sb2O3 (C), or 1 μmol/L PAT (D) were bound to poly-Lysine treated coverslips, fixed and stained with Hoechst 33258. Apoptotic cells show chromatin condensation and micronuclei.

Trivalent antimonials induce apoptosis of APL cells. Untreated NB4 cells (A) or cells treated for 24 hours with either 1 μmol/L As2O3 (B), 1 μmol/L Sb2O3 (C), or 1 μmol/L PAT (D) were bound to poly-Lysine treated coverslips, fixed and stained with Hoechst 33258. Apoptotic cells show chromatin condensation and micronuclei.

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