Proportions (top panels) and absolute numbers (bottom panels) of lymphocyte subsets identified by CD45 isoform expression among CD4⁺ (left) and CD8⁺ (right) cells after BMT from MUD. Progressive appearance of CD45RA⁺cells (•) and reciprocal decrease of the proportion of cells with CD45R0⁺ phenotype (□). Lines represent the result of regression analyses for CD45RA⁺ (—) and CD45R0⁺ cells (---). The absolute number of CD45RA⁺ cells (white) increases progressively whereas that of CD45R0⁺ cells remains fairly constant (gray). Boxes represent 25th-75th percentile and horizontal lines within boxes represent the median. HC, healthy controls.