Fig. 6.
![Fig. 6. Endothelial IL-8 suppressed growth of subcutaneous K562 cell tumors. The subepiderms of nude mice (10 examined per group) were inoculated K562 cells, and agents were injected with endothelial IL-8 (IL-8 [E]), monocyte-derived IL-8 (IL-8 [M]), saline, and TNF- daily as described in Materials and Methods. As controls, monocyte-derived IL-8, saline, and TNF- were used. Data shown come from 10 nude mice. Statistical analysis was performed using the Student’s t-test. In (B), *P < .05 and **P< .005. (A) Photograph of suppression of subcutaneous K562 tumor by endothelial IL-8 (IL-8 [E]). As controls, saline, monocyte-derived IL-8 (IL-8 [M]), and TNF- were used.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/92/8/10.1182_blood.v92.8.2672/5/blod42040006w.jpeg?Expires=1725024622&Signature=CrQkFo4OeLINP4WdSdWtSDWDCKF8aRFY2x0r1fbDtQYWII7qSeNhRkaaxPQYOxnqpIqv9nB3C~EVo2tGqqxoYda8SHwSZlDAfUiK9HBNCfR-00AeopE2oz1O0cdvoe98fAPxal8C1Q117-L7d1a8z2Jyr5GtZIsgbUHl39ZVSL8ssqLd8UMl~itAjpkJXR10AlDFTVejge55KbsoOmnqub~T5D8Tr3MAeeFraZFXCIWXdREQi~lWR~kdzvbNhdqFyj-mko5jRuWxtV5jxe1jsyDz3WSszzeWxUuRjbMt0h2-H4bHiTJDPLy9Dcd6RjURs7dX53kAXVJ-7FqXu6J~~Q__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Endothelial IL-8 suppressed growth of subcutaneous K562 cell tumors. The subepiderms of nude mice (10 examined per group) were inoculated K562 cells, and agents were injected with endothelial IL-8 (IL-8 [E]), monocyte-derived IL-8 (IL-8 [M]), saline, and TNF- daily as described in Materials and Methods. As controls, monocyte-derived IL-8, saline, and TNF- were used. Data shown come from 10 nude mice. Statistical analysis was performed using the Student’s t-test. In (B), *P < .05 and **P< .005. (A) Photograph of suppression of subcutaneous K562 tumor by endothelial IL-8 (IL-8 [E]). As controls, saline, monocyte-derived IL-8 (IL-8 [M]), and TNF- were used.
