Fig. 5.
Fig. 5. (A and B): Predictive value of sL-selectin or leukocyte count for OS (A) or EFS (B). The x-axes indicate the number of patients that would be classified in the low-risk group for a certain cut-point (we used 9 cut-points, each with increment of 10 cases, starting from 10 patients). Because of ties in the leukocyte values, the first groups contain slightly more or less than 10 cases. On the y-axes, logrank statistic numerators (O-E) for these 9 cut-points for sL selectin (continuous line) and leukocyte (dotted line) where the outcome is OS (A) and EFS (B). The left part of each graph represents cut-points that classify few people in a good-risk and many in a poor-risk group. The right part of each graph represents cut-points that classify many people in a good-risk and few in a poor-risk group. A large value on y-axes implies that the marker discriminates well between good- and poor-risk patients using the respective cut-off point. As the graphs indicate, sL-selectin was superior to leukocyte counts in prognostic value for all 9 cut-offs for OS (P = .001) and EFS (P= .0001).

(A and B): Predictive value of sL-selectin or leukocyte count for OS (A) or EFS (B). The x-axes indicate the number of patients that would be classified in the low-risk group for a certain cut-point (we used 9 cut-points, each with increment of 10 cases, starting from 10 patients). Because of ties in the leukocyte values, the first groups contain slightly more or less than 10 cases. On the y-axes, logrank statistic numerators (O-E) for these 9 cut-points for sL selectin (continuous line) and leukocyte (dotted line) where the outcome is OS (A) and EFS (B). The left part of each graph represents cut-points that classify few people in a good-risk and many in a poor-risk group. The right part of each graph represents cut-points that classify many people in a good-risk and few in a poor-risk group. A large value on y-axes implies that the marker discriminates well between good- and poor-risk patients using the respective cut-off point. As the graphs indicate, sL-selectin was superior to leukocyte counts in prognostic value for all 9 cut-offs for OS (P = .001) and EFS (P= .0001).

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