hIg levels in SCID-hu mice. The mice were bled at the indicated time point after inoculation of myeloma cells, and the levels of Ig heavy and light chains were determined by ELISAs. Three examples are presented. (A) IgGκ myeloma (patient no. 1). (B) IgAκ myeloma (patient no. 2). (C) κ light chain myeloma (patient no. 6).