Representative example of long-term Ig therapy in a patient with IgG-MGUS FVIII/vWF measurements ([▵] FVIII; [•] vWF:Ag; [○] vWF:RCo) before and at various times after repeated infusion of high-dose Ig. Arrows at the top indicate the infusion of different concentrations of Ig: 1 g/kg (solid, long arrow), 0.75 g/kg (solid, short arrow), and 0.5 g/kg (hatched, short arrow). Note that the response of FVIII/vWF measurements is consistent when 1 g/kg Ig is used but is lower when the dosage is tapered.